Education

• B.Sc. Pharmaceutical Chemistry. Universidad Autónoma de Yucatán. 1991
• Ph.D. Southern Cross University, Australia. 2002
• Post-doctorate. Centro de Investigación Biomédica-IMSS, México. 2004

Current research

• Natural Products Biotechnology

ONGOING PROJECTS

• Isolation and Antiviral Evaluation of the Components Present in Diospyros anisandra and Caesalpinnia yucatanensis. (CONACYT CIENCIA BÁSICA)
• Evaluation of Compounds from the Native Flora of the South-Southeast Region of Mexico with Potential Antiviral Activity Against the AH1N1 Influenza Virus. (CONACYT FONDO SECTORIAL SALUD)
• Obtaining Products of Pharmaceutical Interest from Aloe Vera Agricultural and Industrial Waste. (FOMIX GOBIERNO DEL ESTADO DE YUCATAN- CONACYT)

RECENT PUBLICATIONS

• Diospyros anisandra phytochemical analysis and anti-hemagglutinin-neuraminidase activity on influenza AH1N1pdm09 virus. Mari Toña Juárez-Méndez, Rocío Borges-Argaez, Guadalupe Ayora-Talavera, Sigfredo Edmundo Escalante-Rebolledo, Fabiola Escalante-Erosa, Mirbella Cáceres-Farfán. Natural Product Research (2021), https://doi.org/10.1080/14786419.2021.1917568.
• Cytotoxic and antiproliferative studies of isocordoin and some derivatives against prostate cancer cell lines. Alejandro Yam-Puc, Rocío Borges-Argáez, Rosa Moo-Puc, Mirbella Cáceres- Farfán (2021) International Journal of Pharmaceutical Science and Research. In press. DOI link: http://dx.doi.org/10.13040/IJPSR.0975-8232.12(8).4160-66.
• Zeylanone epoxide isolated from Diospyros anisandra stem bark inhibits influenza virus in vitro. Lisseth Cetina-Montejo, Guadalupe Ayora-Talavera, Rocío Borges-Argáez. Archives of Virology (2019) 164: 1543-1552. Impact factor: 2.261. https://doi.org/10.1007/s00705-019-04223-y.
• In vitro evaluation of anthraquinones from Aloe vera (Aloe barbadensis Miller) roots and several derivatives against strains of influenza virus. Rocío Borges-Argáez, Reyna Chan-Balan, Lisseth Cetina-Montejo, Guadalupe Ayora-Talavera, Pablo Sansores-Peraza, Jesús Gómez-Carballo, Mirbella Cáceres-Farfán. Industrial Crops and Products 132 (2019) 468-475. Impact factor: 3.80 https://doi.org/10.1016/j.indcrop.2019.02.056.
• Extraction of phenolic components from an Aloe vera (Aloe barbadensis Miller) crop and their potential as antimicrobials and textile dyes. Gonzalo Canché-Escamilla, Pamela Colli-Acevedo, Rocío Borges-Argáez, Patricia Quintana-Owen, J. Fernando May-Crespo, Mirbella Cáceres-Farfán, Jesús Alejandro Yam-Puc, Pablo Sansores-Peraza, Blanca Marina Vera-Ku. (2019) Sustainable Chemistry and Pharmacy 14 (2019), 100168. Impact factor: 2.40 https://doi.org/10.1016/j.scp.2019.100168.

PATENTS OR TECHNOLOGICAL DEVELOPMENTS

• Pharmaceutical composition comprising a standardized extract of Lonchocarpus punctatus as a natural larvicidal control and hatching inhibitor of Rhipicephalus (Boophilus) microplus tick larvae susceptible and resistant to organophosphates, pyrethroids and amidines. Patent application published in the IMPI Gazette, GRANTED. May 2016, MX/a/2011/013047.
• Use of dimeric naphthoquinones in the treatment and control of drug-resistant tuberculosis Patent application published in the IMPI Gazette August 2018, application MX / a / 2013/005302. GRANTED. July 2019, MX366475B.
• Use of naphthoquinones for the treatment of influenza. Under examination, January 2017. Mx / a / 2017/000486. Instituto Mexicano de la Propiedad Intelectual (IMPI).

RECOGNITIONS AND AWARDS

• 1991. Syntex Award. Best undergraduate thesis in Pharmaceutical Biological Chemistry. Universidad Autónoma de Yucatán.
• 2010. Recognition. Advisor to Teresita Vela-Catzín, M.S., First Place, best Master’s thesis in Chemical Sciences, national level. Sociedad Química de México.
• 2012. Recognition. Advisor to Azucena Chuc-Koyoc, best undergraduate thesis in Industrial Chemical Engineering. Universidad Autónoma de Yucatán and BMedina.
• 2014. Recognition. Advisor to Lisseth Abigail Cetina-Montejo, best undergraduate thesis in Pharmaceutical Biological Chemistry. Universidad Autónoma de Yucatán.
• 2014. Recognition. Advisor to Pamela Alejandra Collí-Acevedo, best undergraduate thesis in Industrial Chemical Engineering. Universidad Autónoma de Yucatán and BMedina.

RECOGNITIONS AND AWARDS

• Academia Mexicana de Ciencias.
• American Chemical Society.
• Sociedad Química de México.
• American Society of Pharmacognosy