Estadistics

50 Publications
13 Students
1 biotechnological product
3 Awards

ABOUT ME

RESEARCH SCIENTIST

Biotechnology department
Scientific Research Center of Yucatán (CICY)
Mérida, Yucatán, México

CURRENT RESEARCH TOPICS

I am focus on the study of epigenetic mechanisms:
DNA methylation, histone modifications and miRNAs
during different plant in vitro culture systems.

CONTACT INFORMATION

Phone: +(52)999 9428330 ext. 310
Fax: +(52)999 9813900
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Unidad de Biotecnología
Centro de Investigación Científica de Yucatán
Calle 43 No. 130 x 32 y 34
Chuburná de Hidalgo, 97205
Mérida, Yucatán, México
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PUBLICATIONS

2020
  • Soto-Cardinault C.; Duarte-Aké F.; De-la-Peña C.; Góngora-Castillo E. (2020). DNA methylation and transcriptomic next generation technologies in cereal genomics. Luis Vaschetto (Ed.). Cereal Genomics: Methods and Protocols. Springer. pp. 65-84
  • Hernández-Castellano S.; Garruña-Hernández R.; Us-Camas R.; Ku-González A.; De-la-Peña C. (2020). Agave angustifolia albino plantlets lose stomatal physiology function by changing the development of the stomatal complex due to a molecular disruption. Molecular Genetics and Genomics. In press
2019
  • Duarte-Aké F.; Us-Camas R.; Cancino-García V.J.; De-la-Peña C. (2019). Epigenetic changes and photosynthetic plasticity in response to environment. Environmental and Experimental Botany 159(3):108-120
  • Méndez-Hernández H.A.; Ledezma-Rodríguez M.; Avilez-Montalvo R.N.; Juárez-Gómez Y.L.; Skeete A.; Avilez-Montalvo J.; De-la-Peña C.; Loyola-Vargas V.M. (2019). Signaling overview of plant somatic embryogenesis. Frontiers in Plant Science 10(77):1
  • Hernández-Castellano S.; De-la-Peña C. (2019). Detection of histone modifications caused by miRNAs. Stefan de Folter (Ed.). Plant MicroRNAs - Methods and Protocols. Springer Science. New York. pp. 347-357
  • Duarte-Aké F.; Nic-Can G.; De-la-Peña C. (2019). Somatic embryogenesis: polycomb complexes control cell-to-embryo transition. R. Alvarez-Venegas, C. De-la-Peña J.A. Casa-Mollano (Eds.). Epigenetics in Plants of Agronomic Importance: Fundaments and Applications, 2nd edition. Springer Switzerland. pp. 339-354
  • Alvarez-Venegas R.; De-la-Peña C.; Casa-Mollano J.A. (2019). Epigenetics in Plants of Agronomic Importance: Fundaments and Applications, 2nd edition. Springer-Verlag
2018
  • Morales-Lara D.; De-la-Peña C.; Murillo-Rodríguez E. (2018). Dad`s snoring may have left molecular scars in your DNA: The emerging role of epigenetics in sleep disorders. Molecular Neurobiology 55(4): 2713-2724
  • Osorio-Montalvo P.; Sáenz-Carbonell L.; De-la-Peña C. (2018). 5-Azacytidine: A promoter of epigenetic changes in the quest to improve plant somatic embryogenesis. International Journal Molecular Science 2018, 19(10), 3182
  • De-la-Peña C. (2018). La epigenética y la reivindicación de Lamarck. Desde el Herbario CICY. 10: 132-136
  • Murillo-Rodríguez E.; Morales-Lara D.; Pastrana-Trejo J.C.; Macías-Triana L.; Romero-Cordero K.; De-la-Peña C. (2018). Canabinoids, sleep and the MCH system. S.R. Pandi-Perumal, Pablo Torterolo, Jaime M. Monti (Eds.). Melanin-Concentrating Hormone and Sleep. Molecular, Functional and Clinical Aspects. Springer-Verlag. Switzerland. pp 121 – 130
  • Us-Camas R.; De-la-Peña C. (2018). Chromatin immunoprecipitation (ChiP) protocol for the analysis of gene regulation by histone modifications in Agave angustifolia Haw. Victor M. Loyola-Vargas and Neftalí Ochoa-Alejo (Eds.). Plant Cell Culture Protocols. Humana Press. New York. pp 371-383
2017
  • Morales-Lara D.; De-la-Peña C.; Murillo-Rodríguez E. (2017). Dad`s snoring may have left molecular scars in your DNA: The emerging role of epigenetics in sleep disorders. Molecular Neurobiology. In press
  • Hernández-Castellano S.; Nic-Can G.; De-la-Peña C. (2017). Localization of miRNAs by in situ hybridization in plants using oligonucleotide conventional probes. Igor Kovalchuk (Ed.). Plant Epigenetics: Methods and Protocols, 2nd edition. Springer-Verlag. Berlín. pp 51 – 62
  • De-la-Peña C.; Nic-Can G.; Avilez-Montalvo J.; Cetz-Chel J.; Loyola-Vargas VM. (2017). The role of miRNAs in auxin signaling and regulation during plant development. Jan Barciszewski (Ed.). Plant Epigenetics, 1st edition. Springer-Verlag. Berlín. In press
  • De-la-Peña C.; Loyola-Vargas V. M. (2017). De la genética a la epigenética. La Ciencia para Todos. Fondo de Cultura Económica. Libro En prensa
2016
  • Alvarez-Venegas R.; De-la-Peña C. (2016). Editorial: Recent advances of epigenetics in crop biotechnology. The editorial on the research topic. Frontiers in Plant Science 7: 413
  • Duarte-Aké F.; Castillo-Castro E.; Barredo Pool F.; Espadas F.; Santamaría J.M.; Robert M.L.; De-la-Peña C. (2016). Physiological differences and changes in global DNA methylation levels in Agave angustifolia Haw. albino variant somaclones during the micropropagation process. Plant Cell Reports 35(12): 2489–2502
  • Duarte-Aké F.; De-la-Peña C. (2016). Epigenetic advances in somatic embryogenesis in sequenced genome crops. Victor M. Loyola-Vargas and Neftalí Ochoa-Alejo (Eds.). Somatic Embryogenesis: Fundamental Aspects and Applications, 1st edition. Springer International. Switzerland. pp 81 – 102
  • De-la-Peña C.; Alvarez-Venegas R.; Cullis C. (2016). Recent advances of epigenetics in crop biotechnology. Frontiers in Plant Science. eBook on line
2015
  • Nic-Can G.; Galáz-Ávalos RM; De-la-Peña C.; Alcazar-Magaña A.; Wrobel K.; Loyola-Vargas VM. (2015). Somatic embryogenesis: Identified factors that lead to embryogenic repression. A case of species of the same genus. PloS One 10(6): e0126414
  • De-la-Peña C.; Nic-Can G.; Galáz-Ávalos RM; Avilez-Montalvo R.; Loyola-Vargas VM. (2015). The role of chromatin modifications in somatic embryogenesis in plants. Frontiers in Plant Science 6: 635
2014
  • Us-Camas R.; Rivera-Solís G.; Duarte-Aké F. De-la-Peña C. (2014). In Vitro Culture: an Epigenetic Challenge for Plants. Plant Cell Tissue and Organ Culture 118(2): 187-201 http://link.springer.com/article/10.1007/s11240-014-0482-8
  • De-la-Peña C.; Loyola-Vargas V. M. (2014). Biotic interactions in the rhizosphere: a diverse cooperative enterprise for plant productivity. Plant Physiology 166(2) http://dx.doi.org/10.1104/pp.114.241810
  • Nic-Can G.; De-la-Peña C. (2014). Epigenetic advances on somatic embryogenesis of agronomical and important crops. R. Alvarez-Venegas, C. De-la-Peña J.A. Casa-Mollano (Eds.). Epigenetics in Plants of Agronomic Importance: Fundaments and Applications, 1st edition. Springer-Verlag. Berlín. pp 91- 109 http://dx.doi.org/10.1007/978-3-319-07971-4_6
  • Alvarez-Venegas R.; De-la-Peña C.; Casa-Mollano J.A. (2014). Epigenetics in Plants of Agronomic Importance: Fundaments and Applications, 1st edition. Springer-Verlag. http://dx.doi.org/10.1007/978-3-319-07971-4
2013
  • Nic-Can G.; López-Torres A.; Barredo-Pool F.; Wrobel K.; Loyola-Vargas V.M.; Rojas-Herrera R.; De-la-Peña C. (2013). New insights into somatic embryogenesis: LEAFY COTYLEDON1, BABY BOOM1 and WUSCHEL-RELATED HOMEOBOX4 are epigenetically regulated in Coffea canephora. PloS One 8(8): e72160. http://dx.doi.org/10.1371/journal.pone.0072160
  • Nic-Can G.; Hernández-Castellano S.; Kú-González, A.; Loyola-Vargas VM; De-la-Peña C. (2013). An efficient immunodetection method for histone modifications in plants. Plant Methods 9:47 http://www.plantmethods.com/content/9/1/47
2012
  • De-la-Peña C.; Nic-Can G.; Ojeda G.; Herrera-Herrera J.S.; López-Torres A.; Wrobel K.; Robert-Díaz M. (2012). KNOX1 is expressed and epigenetically regulated during in vitro conditions in Agave spp. BMC Plant Biology 12(1): 203.
  • Badri D. V.; De-la-Peña C.; Chaparro J.; Lei Z.; Manter D.K.; Guimaraes R.; Sumner L. W.; Vivanco J.M. (2012). Root secreted metabolites and proteins are involved in the early events of plant-plant recognition prior to competition. PloS One 7(10): e46640.  http://dx.doi.org/10.1371/journal.pone.0046640
  • loyola-vargas VM; De-la-Peña C. (2012). The role of jasmonic acid in root mitochondria disruption. Plant Signalling & Behaviour 7(6): 611-614.  http://dx.doi.org/10.4161/psb.20070
  • De-la-Peña C.; Loyola-Vargas V. M. (2012). The hidden chemical cross-talk between roots and microbes: A proteomic approach. Current Proteomics 9(2): 103-117
  • Mukul-López H.G.; De-la-Peña C.; Galaz-Ávalos R.M.; Loyola-Vargas V.M. (2012). Evaluation of the extracellular proteome profile during indirect somatic embryogenesis process of Coffea arabica. Journal of the Mexican Chemical Society 56(1): 72-79
  • De-la-Peña C.; Rangel-Cano A.; Alvarez-Venegas R. (2012). Regulation of disease responsive genes mediated by epigenetic factors: interaction Arabidopsis-Pseudomonas. Molecular Plant Pathology 13(4): 388-398.  http://dx.doi.org/10.1111/j.1364-3703.2011.00757.x
  • De-la-Peña C.; Badri D. V.; Loyola-Vargas V. M. (2012). Plant root secretions and their interactions with neighbors. Jorge Vivanco and František Baluška (Eds.). Secretions and Exudates in Biological Systems (Signaling and Communication in Plants). Springer-Verlag. Berlin. pp 1-26. http://dx.doi.org/10.1007/978-3-642-23047-9_1
  • Nic-Can G.; De-la-Peña C. (2012). Determination of histone methylation in mono- and dicotyledons plants. V.M. Loyola-Vargas and N. Ochoa-Alejo (Eds.). Plant Cell Culture Protocols, 3er edition. Humana Press. London. pp 313-324. http://dx.doi.org/10.1007/978-1-61779-818-4_24
2011
  • Ruiz-May E.; De-la-Peña C.; Galaz-Ávalos R.M.; Lei Z.; Watson B. S.; Sumner L. W.; Loyola-Vargas V. M. (2011). Methyl jasmonate induces ATP biosynthesis deficiency and accumulation on proteins related to secondary metabolism in Catharanthus roseus (L.) G. hairy roots. Plant and Cell Physiology 52(8): 1401-1421.  http://dx.doi.org/10.1093/pcp/pcr086
  • De-la-Peña C.; Vivanco J.M. (2011). Proteins in the rhizosphere: another example of plant-microbe exchange. Joe Polacco and Chris Todd (Eds.). Ecological aspects of nitrogen metabolism in plants. Wiley-Blackwell. USA, pp 95-116.  http://dx.doi.org/10.1002/9780470959404.ch5
2010
  • De-la-Peña C.; Vivanco J. M. (2010). Root-microbe interactions: the importance of protein secretion. Current Proteomics 7(4): 265-274
  • De-la-Peña C.; Badri D. V.; Lei Z.; Watson B. S.; Brandao M. M; Silva-Filho M. C.; Sumner L. W.; Vivanco J. M. (2010). Root secretion of defense-related proteins is development-dependent and correlated with flowering time. Journal of Biological Chemistry 285(40): 30654-30665.  http://dx.doi.org/10.1074/jbc.M110.119040
  • Broz A. K.; Broeckling C. D.; De-la-Peña C.; Lewis M.; Greene E.; Callaway R.; Sumner L. W.; Vivanco J. M. (2010). Plant neighbor identity influences plant biochemistry and physiology related to defense. BMC Plant Biology 10: 115. http://dx.doi.org/10.1186/1471-2229-10-115 
  • Ruiz-May E.; De-la-Peña C.; Ayil-Gutiérrez B.A.; Nic-Can G.I.; Mukul-López, H.G.; Galaz-Ávalos R. M.; Loyola-Vargas V. M. (2010). Protein secretion by cell cultures: an essential biological issue. Acta Horticulturae 849: 213-222. http://www.actahort.org/books/849/849_23.htm
2008
  • De-la-Peña C.; Lei Z.; Watson B. S.; Sumner L. W.; Vivanco J. M. (2008). Root-microbe communication through protein secretion. Journal of Biological Chemistry 283(37): 25247-25255. http://dx.doi.org/10.1074/jbc.M801967200
  • De-la-Peña C.; Galaz-Ávalos R. M.; Loyola-Vargas V. M. (2008). Possible role of light and polyamines in the onset of somatic embryogenesis of Coffea canephora. Molecular Biotechnology 39(3): 215-224. http://dx.doi.org/10.1007/s12033-008-9037-8
  • De-la-Peña C.; Badri D. V.; Vivanco J. M. (2008). Novel role for pectin methylesterase in Arabidopsis: a new function showing ribosome-inactivating protein (RIP) activity. Biochimica et Biophysica Acta: General Subjects 1780: 773-783.
  • Badri D. V.; Loyola-Vargas V. M.; Broeckling, C. D.; De-la-Peña C.; Jasinski M.; Santelia D.; Martinoia E.; Sumner L. W.; Banta L. M.; Stermitz F.; Vivanco J. M. (2008). Altered profile of secondary metabolites in the root exudates of Arabidopsis ATP-binding cassette (ABC) transporter mutants. Plant Physiology 146(2): 762-771.
  • Loyola-Vargas V. M.; De-la-Peña C.; Galaz-Ávalos R. M.; Quiroz-Figueroa F. R. (2008). Plant tissue culture. An intemporal set of tools. J.M. Walker and M. Rapley (Eds.). Molecular Biomethods Handbook, 2nd edition. Springer-Verlag. Berlin, pp 873-901

RESEARCH

Our current focus is on the molecular mechanisms of epigenetics: DNA methylation, histone posttranslational modifications and miRNAs during different plant in vitro culture systems. Because of continually increasing world population, the continued production of enough food and energy is a basic challenge. Two of the critical factors that determine crop productivity are the efficient germination of seeds and the number of plants per hectare. In order to achieve good growth and development, plants need the normal and efficient development of the embryo inside the seed. In addition, in cultivars that have long wait between germination and reproduction, it has been necessary to use propagation techniques in vitro to genetically improve and enhance the crop productivity to satisfy the market demand. One of the most common approaches to circumvent food production limits is the use of in vitro scaling-up techniques that lead to the production of high numbers of high-quality plant embryos in vitro. Agave and coffee are two of the most important agricultural products that benefit from programs of in vitro plant development and plant breeding.

Research

Our lab is interested to investigate the gene regulation involved during the somatic embryogenesis process in coffee and agave micropropagation using epigenetics. The importance of epigenetic studies in agriculture need to be addressed, because these could have an important impact on food supply programs that are necessary to cope with the consequences of global climate change. We are analyzing specific modifications in developing somatic embryos, with the goal of elucidating regulatory epigenetic mechanisms that underlie seed germination in recalcitrant plants. Furthermore, we want to know the principal epigenetic mechanisms influencing in vitro cultures to maximize production of high quality plant varieties.

Research

Our most recent project is about the role of epigenetics on somaclonal variation in Agave. We have found that DNA methylation could be the trigger of chlorophyll deficiency during the in vitro culture of Agave.

Research

MAIN PROJECTS

Meet Our Team

CLELIA DE LA PEÑA PROFESSOR, GROUP P.I. professor A SNI 2.
I am focus on the study of epigenetic mechanisms: DNA methylation, histone modifications and miRNAsduring different plant in vitro culture systems.
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EDUARDO CASTILLO LAB MANAGER Associate technician C
This email address is being protected from spambots. You need JavaScript enabled to view it. I am involved in a variety of laboratory-based investigation related to epigenetics. I carry out sampling, measuring, recording and analyzing of results in the Agave micropropagation projects.
FÁTIMA DUARTE PHD STUDENTS This email address is being protected from spambots. You need JavaScript enabled to view it.
Epigenetic changes including DNA methylation, covalent histone modification and microRNAs are result of in vitro plant tissue culture,...
ROSA US CAMAS PHD STUDENTS This email address is being protected from spambots. You need JavaScript enabled to view it.
Albinism in nature is quite rare and although genetic clues have been important to understand the basis of this phenomenon...
SARA HERNÁNDEZ CASTELLANO PHD STUDENTS This email address is being protected from spambots. You need JavaScript enabled to view it.
INÉS ARANA GUEVARA PHD STUDENTS This email address is being protected from spambots. You need JavaScript enabled to view it.

Proyecto Biotecnológico

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